telomare

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= __Definition:__ =

A string of repetitive DNA at the tip of each chromosome in the body that appears to serve as a kind of timekeeping mechanism HGD Chapter 17 pp. 441.

= __Examples:__ =


 * Telomere shortening cannot be the only mechanism involved in aging at the cellular level.
 * Telomere length in families from northern belgium.
 * Telomere maintenance is essential for tumor cells to by-pass replicative senescence and become immortal.
 * Telomere dysfunction promote genomic instability and drives development of the disease.
 * One of the current models suggests that during the early stages of cancer telomere erosion leads to short dysfunctional telomere erosion leads to short dysfunctional telomeres
 * Telomere dynamics.





= __Analogies:__ = Telomere are like the last 2" of a pencil... an extension of the rest. Not used to write with, but rather just to hold on to while writing, and is thrown away after the rest of the pencil is used.

= __Mnemonics:__ =

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