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=DARPA taps Lawrence Livermore to develop world's first neural device to restore memory. =

The Neural Technology group will seek to develop a neuromodulation system -- a sophisticated electronics system to modulate neurons -- that will investigate areas of the brain associated with memory to understand how new memories are formed. The device will be developed at LLNL's Center for Bioengineering. The research builds on the understanding that memory is a process in which neurons in certain regions of the brain encode information, store it and retrieve it. Certain types of illnesses and injuries, including Traumatic Brain Injury (TBI), Alzheimer's disease and epilepsy, disrupt this process and cause memory loss. TBI, in particular, has affected 270,000 military service members since 2000. Using the Center for Bioengineering's capabilities, Pannu and his team of engineers have achieved 25 patents and many publications during the last decade. The team's goal is to build the new prototype device for clinical testing by 2017. Designed to last throughout the duration of treatment, the device's electrodes will be integrated with electronics using advanced LLNL integration and 3D packaging technologies. The microelectrodes that are the heart of this device are embedded in a biocompatible, flexible polymer. LLNL will develop a miniature, wireless and chronically implantable neural device that will incorporate both single neuron and local field potential recordings into a closed-loop system to implant into TBI patients' brains. The device -- implanted into the entorhinal cortex and hippocampus -- will allow for stimulation and recording from 64 channels located on a pair of high-density electrode arrays. The entorhinal cortex and hippocampus are regions of the brain associated with memory.

References: The above story is based on materials  provided by **DOE/Lawrence Livermore National Laboratory** . //Note: Materials may be edited for content and length. //

DOE/Lawrence Livermore National Laboratory. "DARPA taps Lawrence Livermore to develop world's first neural device to restore memory." ScienceDaily. ScienceDaily, 10 July 2014. .

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