Fragile-X+Syndrome

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= = = __Definition__: Fragile- X Syndrome =

A sex- linked disorder in which a person has an X chromosome with a "fragile" or damaged spot. p56 HGD Chapter 3 1 in every 4,000 males and 1 in every 8,000 females have this disorder.

Fragile X-syndrome can cause mental retardation that becomes progressively worse as a child gets older.



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=__In the News__= __[|Experimental drug to treat fragile X syndrome shows promise]__ An experimental drug designed to treat a genetic condition that is the most common cause of inherited mental retardation helped patients develop better social skills, according to a small study published in a major medical journal Wednesday. The drug is still in an early stage of development, but its success gives researchers courage to move on to larger trials that may lead to a filing for approval with the Food and Drug Administration.

[|Study Links Fragile X Syndrome To 93 Different Autism Genes] Researchers from Duke University Medical Center and Rockefeller University recently discovered that the gene responsible for fragile X syndrome is connected to almost 100 other genes that have been linked to autism. While researchers have long been aware of a relationship between fragile X syndrome and autism, this is the first time that they have begun to trace out the exact genetic pathways that link the two disorders together.

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